Iris Pharma offers nearly 50 in vivo animal models – the largest number on the market – to mimic conditions of the human eye. Not only do we help clients select the appropriate in vivo efficacy model, but we can also develop new animal models as needed, according to the specific requirements of our clients.
We use state-of-the-art ocular technology – including Spectralis® HRA+OCT, confocal microscopy, tomography, electroretinography, and more – to demonstrate the efficacy of particular ophthalmic drugs or devices.
Intraocular pressure (IOP) measurement (tonometry)
Graph legend: Reduction of experimentally induced elevated intraocular pressure (IOP)
Graph legend: Conjunctival extravasation of dye in sensitized animals using the antigen challenge model
Graph legend: Changes in tear migration after one instillation
Graph legend: Rate of corneal wound healing after complete deepithelialization and daily instillation