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Diabetic retinopathy

Models:

  • Retinal vascular permeability: VEGF-induced fluorescein leakage
  • Retinal angiogenesis: animal model of oxygen-induced retinopathy (OIR)

Applications:

  • Retinal vascular edema (diabetic macular edema, retinal vein occlusion)
  • Diabetic retinopathy (retinal angiogenesis)
  • Human retinopathy of prematury (ROP)

Administrations: topical ocular administration, intraviteal injection, intraperitoneal, sub-cutaneous injection 

 

Animals: pigmented rabbits, mice

 

Evaluations:

  • In vivo retinal fluorescein leakage using scanning fluorophotometry
  • Histology

Reference substances: triamcinolone acetonide, dexamethasone, ranibizumab

 

If you need more information on others Iris Pharma’s animal models of Diabetic Retinopathy, please contact us at info@iris-pharma.com or call 33 4 93 59 49 59