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ANIMAL MODELS

• EYE DISCOMFORT : March 2010 - A more ethical eye discomfort model to test the efficacy of your compounds in reducing mild ocular pain […] more
• RETINAL DEGENERATION : March 2010 - A new model of blue ligh-induced damage at Iris Pharma targeting the neuroprotection effect […] more
• DRY EYE MODEL : February 2009 - A new dry eye model in albino rabbits to add to its catalog of animal models designed for preclinical testing in the field of ophthalmology. This dry eye model in rabbits is induced by repeated daily instillations of 1.0% atropine sulfate. The model produces rapidly some typical dry eye symptoms such as a significant reduction in tear volume, Tear Break-Up Time (TBUT), corneal staining and histopathological signs of dryness and inflammation […] Read the newsletter (html)
• OCULAR INFLAMMATION MODEL : December 2008 - A rat Experimental Autoimmune Uveitis (EAU) model has been developed by the Iris Pharma Research Team. Experimental Autoimmune Uveitis (EAU) is an organ-specific autoimmune disease and serves as a model of certain ocular inflammatory pathologies in human […] Read the newsletter (html)
• AGE-RELATED MACULAR DEGENERESCENCE AND RETINAL DEGENERESCENCE MODELS : June 2006 - The Iris Pharma Research Team has validated several animal models to investigate the various aspects of Age-related Macular Degenerescence (AMD) and retinal degenerescence: corneal angiogenesis (suture model on rabbits), retinopathy of prematurity (ROP, hyperoxia model in pup mice), chemical burn (alcohol, sodium hydroxyde models in rats, mice and rabbits), retinal vascular permeability (VEGF-induced leakage) in rabbits and choroidial neovascularization (CNV) model. […] Read the press release (html). Read the press release (pdf)

SURGICAL TECHNIQUE

• PARTIAL VITRECTOMY : January 2010 - Our technicians have successfully performed partial vitrectomies in rabbits […] Read the newsletter (html)

 

ACCREDITATION

• CIR ACCREDITATION HAS BEEN RENEWED : March 2010 - Attractive tax measures with Iris Pharma […] Read the newsletter (html)

 

METHODS

• Evaluation of the volume of the lesion in the Choroidal Neovascularization (CNV) using endothelial cell specific staining (anti-isolectine B4).
• Evaluation of animal model allergic conjunctivitis using in vivo confocal microscopy (HRTII) and conjunctival impression cytology collection.

 

ACQUISITIONS (APPARATUS)

• Acquisition of a new RRLC-MS/MS system for clearly superior results in bioanalysis
  After a one-year trial period, Iris Pharma had acquired the Agilent 6410 triple quadrupole LCMS. This system dramatically increases the speed of analysis, the volume of sample and the sensitivity and brings the highest level of performance and reliability to Iris Pharma labs.
• Counter beta Tri-Carb 2900 (Perkin Elmer): liquid scintillation analyzer. This instrument measures levels of radioactive elements by counting photonic emissions produced when alpha and beta particles interact with certain reagents (scintillants).
• Cyclone Plus Phosphor Imager: radiometric phosphor imager for quantitative filmless autoradiography. ApoTome: light microscope using "structured illumination" process for 3D fluorescence imaging.

NEW PARIS PREMISES AT THE INSTITUT DE LA VISION

December, 2008 - Iris Pharma opens its new Paris (FRANCE) premises at the Institut de la Vision, one of Europe's major research centers dedicated to eye diseases. This collaboration will facilitate the accelerated development of new therapies to benefit patients with impaired vision and suffering from ocular ailments. […] Read the press release Lire le communiqué de presse.

 

PARTNERSHIP

July, 2008 - The Institut de la Vision and Iris Pharma join forces to strengthen the bond between the private and public sectors, and between industry and academic research […] Read the press release

 

MERGER

December, 2007 - Iris Pharma, a specialist CRO for pre-clinical research in ophthalmology, has announced the completion of its merger with Clirophtha, a unique CRO in Europe and North America that is completely dedicated to ophthalmology clinical trials […] Read the press release

PEOPLE

December, 2007 - Dr Mustapha Benchaboune joined Iris Pharma's clinical services staff on November 1st, 2007 as a Medical Director […] Read the press release

NEW ANIMAL HUSBANDRY

December, 2007 - Due to the steady increase in demand for its services, Iris Pharma has decided to expand its animal housing facility […] Read the press release

COMMITMENT

February, 2008 - Establishment of Ophta Biotech
Iris Pharma is one of the co-founders of this new French organization which aims at gathering the French Riviera, Corsica and Monaco-based experts, doctors, industries, researchers, patients organizations and others who have a concern in ophthalmology to better promote the local expertise and know-how in this field around the world. […] Read the press release. Lire le communiqué de presse.