Models:

• retinal vascular permeability: VEGF-induced fluorescein leakage
• retinal angiogenesis / retinopathy of prematurity (ROP): animal model of oxygen-induced retinopathy (OIR)

Administration: topical ocular administration, i.v., i.p.

Animals: albino or pigmented rats, rabbits, mice

Evaluation:

• Glycemia
• Histology
• Fluorescein permeation (fluotron)

Reference substances: corticoids

If you need more information on others Iris Pharma’s animal models of Diabetic Retinopathy, please contact us at info@iris-pharma.com or call 33 4 93 59 49 59