Model:

• streptozotocin-induced diabetes (STZ)
• db/db mice
• retinal vascular permeability: VEGF-induced fluorescein leakage

Administration: topical ocular administration, i.v., i.p.

Animals: albino or pigmented rats, rabbits, mice

Evaluation:

• Glycemia
• Angiography (HRA)
• Electroretinography (ERG)
• Histology
• Fundus (slit lamp, HRT)

Reference substances: dexamethasone

If you need more information on others Iris Pharma’s animal models of diabetic retinopathy, please contact us at info@iris-pharma.com or call 33 4 93 59 49 59